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Company

Cognitive Decline After Surgery and Chemotherapy: The Gap, the Science, and What We’re Building

POCD and CICI are real, named conditions affecting millions each year. There are no approved treatments. This is why we built Nulyn Science.

June 2, 2026 · 8 min read
Science

What Is POCD — and Why Does It Matter?

Up to 30% of older surgical patients experience lasting cognitive decline. Most are never warned. Here’s the biology and what patients can do.

May 19, 2026 · 7 min read
Science

The Science Behind Chemobrain

Cancer survivors have described it for decades. The neuroinflammatory mechanism behind CICI is finally well understood — and it points to a tractable target.

May 5, 2026 · 8 min read
Strategy

The Fastest Path to a Treatment Isn’t Always a New Drug

How drug repurposing changes the economics — and the ethics — of pharmaceutical development, and why 505(b)(2) is the right strategy for POCD and CICI.

April 21, 2026 · 7 min read
Patients

Who Is at Risk for Cognitive Decline After Surgery?

POCD doesn’t happen to everyone. Certain factors — age, procedure type, vascular health — make it significantly more likely. Here’s what the evidence says.

April 7, 2026 · 8 min read
Patients

What Helps with Chemobrain — and What Doesn’t

What has real evidence, what has uncertain magnitude, and what is probably not worth a patient’s energy. A clear-eyed look at the current landscape.

March 24, 2026 · 7 min read
Science

Microglia: The Brain’s Immune Cell That’s Gotten Too Good at Its Job

Understanding the cell at the center of neuroinflammation — and why its dysregulation connects chemobrain, POCD, and Alzheimer’s disease.

March 10, 2026 · 8 min read
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